Acute Kidney Injury
A sudden drop in kidney function over hours or days, often in people who are already unwell.
Quick Summary
Passing less urine, swelling, tiredness, confusion, nausea and breathlessness. Sometimes found only on blood tests.
Treating the cause, correcting fluids and salts, stopping harmful medicines and, if needed, dialysis.
Severe dehydration, infections, low blood pressure, some medicines, older age and existing kidney disease.
Overview
Acute kidney injury (AKI) can happen with severe diarrhoea, serious infections, surgery or after some medicines and dyes.
It can often be reversed if treated quickly, but it can be life-threatening.
Symptoms
Less urine
Passing much less than usual.
Swelling
Legs and ankles.
Confusion
Or drowsiness.
Nausea and tiredness
Feeling generally unwell.
Causes & Risk Factors
Biological Causes
Reduced blood flow to the kidneys, direct kidney damage, or blockage of urine flow.
Key Risk Factors
- Dehydration From vomiting, diarrhoea or heat.
- Medicines NSAIDs, some antibiotics, and contrast dye.
- Existing conditions Diabetes, heart failure and chronic kidney disease.
Management & Treatment
01. Treat the cause
Fluids, antibiotics or relieving a blockage.
02. Medicine review
Stop medicines that harm the kidneys.
03. Dialysis
Temporarily, if needed.
Frequently Asked Questions
Can the kidneys recover?
How is it found?
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Kidney Failure(opens in a new tab) · MedlinePlus, US National Library of Medicine
- Acute kidney injury (AKI)(opens in a new tab) · NHS