Alcohol deterrentPrescription only
Disulfiram
Tablet
Quick Summary
Disulfiram blocks alcohol breakdown, so drinking causes flushing, nausea and palpitations.
Alcohol dependence
Medical Uses
Alcohol dependence: With counselling and support.
How it's taken
Take only with full knowledge and consent, after at least a day without alcohol, under medical supervision.
Your doctor decides the right dose for you and how long to take it.
Your doctor decides the right dose for you. Follow their instructions and the label.
Common Side Effects
Drowsiness
Sometimes.
Metallic taste
Sometimes.
Liver problems
Rarely.
Interactions
Alcohol in any form
Including mouthwashes and some syrups.
Metronidazole and warfarin
Interactions.
Critical Warnings
Alcohol reaction
Black Box Warning: Can be severe and dangerous.
Never given secretly
Black Box Warning: It must be taken with the person's consent.
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Disulfiram: drug information(opens in a new tab) · MedlinePlus, US National Library of Medicine