Anti-sicknessPrescription only
Domperidone
Tablet or suspension
Quick Summary
Domperidone blocks dopamine signals that cause nausea and speeds up stomach emptying.
Nausea and vomiting
Bloating and fullness
Medical Uses
Nausea and vomiting: Short-term.
Bloating and fullness: From slow stomach emptying.
How it's taken
Taken before meals for a short time, usually no longer than a week.
Your doctor decides the right dose for you and how long to take it.
Your doctor decides the right dose for you. Follow their instructions and the label.
Common Side Effects
Dry mouth
Sometimes.
Headache
Sometimes.
Heart rhythm effects
Rare but serious.
Interactions
Heart rhythm medicines
And some antifungals or antibiotics increase rhythm risk.
Critical Warnings
Heart rhythm
Black Box Warning: Can cause irregular heartbeat, especially in older people or with heart disease.
Short-term only
Use for the shortest time possible.
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.