PDE5 inhibitorPrescription only

Tadalafil

Tablet

Quick Summary

Tadalafil increases blood flow to the penis when sexually aroused.

Erectile dysfunction
Enlarged prostate

Medical Uses

Erectile dysfunction: As needed or daily, as prescribed.
Enlarged prostate: Daily low dose.

How it's taken

Take as prescribed, not more than once a day.

Your doctor decides the right dose for you and how long to take it.

Your doctor decides the right dose for you. Follow their instructions and the label.

Common Side Effects

Headache

Common.

Flushing

Common.

Blocked nose

Sometimes.

Interactions

Nitrates such as GTN

Dangerous drop in blood pressure.

Alpha blockers

Low blood pressure.

Critical Warnings

Never with nitrates

Black Box Warning: Can be fatal.

Erection lasting over 4 hours

Black Box Warning: Emergency.

Heart disease

Check with your doctor.

Sources and further reading

Last updated 21 October 2026. For more detail, see these trusted health organisations.