Pulmonology• Updated 21 October 2026

Pleural Fluid Analysis

A test of fluid removed from around the lungs to find the cause, such as TB, infection or cancer.

Results: Same day to a few days Specimen: Pleural fluid

Quick Summary

Primary Purpose

To find the cause of fluid around the lungs and relieve breathlessness.

What It Measures

Protein, cells, ADA, culture and cancer cells.

Preparation

Usually no preparation.

Overview

In India, TB is a common cause; ADA levels help.

Removing fluid can ease breathlessness.

What It Measures

Cells and protein

Cause clues.

ADA

TB marker.

Cytology

Cancer cells.

How It's Performed

  1. 01

    Position

    Sit leaning forward.

  2. 02

    Numb

    Local anaesthetic.

  3. 03

    Needle

    Fluid drawn, often with ultrasound guidance.

Sources and further reading

Last updated 21 October 2026. For more detail, see these trusted health organisations.

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