Sepsis
A life-threatening reaction to an infection, where the body damages its own organs. It needs emergency treatment.
Quick Summary
Fever or very low temperature, fast heartbeat, fast breathing, confusion, cold clammy skin, little urine and feeling extremely unwell.
Emergency antibiotics, fluids and organ support in hospital.
Very young or old age, weak immunity, diabetes, recent surgery, and infections such as pneumonia or UTI.
Overview
Sepsis can start from any infection. Early recognition and treatment save lives.
If someone with an infection becomes suddenly much worse, call 112.
Symptoms
Fever or low temperature
Shivering.
Fast heartbeat
And breathing.
Confusion
Slurred speech or drowsiness.
Little urine
And mottled skin.
Causes & Risk Factors
Biological Causes
An overwhelming immune response to infection.
Key Risk Factors
- Age Babies and older adults.
- Weak immunity Cancer treatment, HIV, diabetes.
- Infections Pneumonia, urinary and tummy infections.
Management & Treatment
01. Antibiotics
Given urgently.
02. Fluids and oxygen
To support the body.
03. Intensive care
For organ support.
Frequently Asked Questions
Is sepsis contagious?
Can sepsis be prevented?
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Sepsis(opens in a new tab) · MedlinePlus, US National Library of Medicine
- Sepsis(opens in a new tab) · NHS