AntimalarialDMARDPrescription only
Hydroxychloroquine
Tablet
Quick Summary
Hydroxychloroquine calms the immune system and reduces flares in lupus and arthritis.
Lupus
Rheumatoid arthritis
Medical Uses
Lupus: Most people take it long term.
Rheumatoid arthritis: Often with other medicines.
How it's taken
Take with food. It takes several weeks to months to work.
Your doctor decides the right dose for you and how long to take it.
Your doctor decides the right dose for you. Follow their instructions and the label.
Common Side Effects
Nausea
And tummy upset.
Rash
Sometimes.
Eye effects
Rare with long use.
Interactions
Heart rhythm medicines
Risk of rhythm problems.
Diabetes medicines
Can lower blood sugar.
Critical Warnings
Eye checks
Regular eye examinations with long-term use.
Heart rhythm
Rarely affects rhythm.
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Hydroxychloroquine: drug information(opens in a new tab) · MedlinePlus, US National Library of Medicine
- Hydroxychloroquine(opens in a new tab) · NHS