Endocrinology• Updated 21 October 2026

Anti-TPO Antibody Test

A blood test for thyroid antibodies that show autoimmune thyroid disease.

Results: A few days Specimen: Blood

Quick Summary

Primary Purpose

To find the cause of hypothyroidism or thyroid swelling.

What It Measures

Thyroid peroxidase antibodies.

Preparation

No preparation.

Overview

Positive antibodies suggest Hashimoto's thyroiditis.

They predict a higher chance of hypothyroidism later.

What It Measures

Anti-TPO

Antibody level.

How It's Performed

  1. 01

    Preparation

    Usually no special preparation unless your doctor advises.

  2. 02

    Blood sample

    A small amount of blood is taken from a vein in your arm.

  3. 03

    Afterwards

    Press on the spot; a small bruise is common.

Reference Ranges

Note: Normal ranges vary by laboratory. Consult your report for the specific reference used.

ParameterTypical Range (Adult)Units
Anti-TPOBelow 35IU/mL

Interpreting Results & Next Steps

Discuss with Doctor

Normal ranges differ between laboratories; use the range on your report. Your doctor will explain what your result means and what happens next.

If values are High:

Raised antibodies suggest autoimmune thyroid disease.

Sources and further reading

Last updated 21 October 2026. For more detail, see these trusted health organisations.

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