Peripheral Neuropathy
Damage to nerves outside the brain and spinal cord, often causing numbness, tingling and pain in the feet and hands.
Quick Summary
Numbness, tingling, burning pain, weakness, loss of balance, and reduced feeling in the feet.
Treating the cause (such as diabetes or B12 deficiency), pain medicines and foot care.
Diabetes, vitamin B12 deficiency, alcohol, some medicines, kidney disease and infections.
Overview
Peripheral nerves carry messages between the brain and the body. When damaged, sensation and movement are affected, usually starting in the feet.
Diabetes is the most common cause. Numb feet are at risk of unnoticed injuries and ulcers.
Symptoms
Numb feet
Often starting in the toes.
Burning pain
Or pins and needles.
Weakness and imbalance
Especially in the dark.
Foot wounds
Unnoticed cuts or ulcers need prompt care.
Causes & Risk Factors
Biological Causes
Nerve damage from high blood sugar, vitamin deficiency, toxins or other diseases.
Key Risk Factors
- Diabetes The leading cause.
- Vitamin B12 deficiency Common in vegetarians and with metformin use.
- Alcohol Long-term heavy drinking.
Management & Treatment
01. Treat the cause
Control blood sugar, replace vitamins, stop alcohol.
02. Pain relief
Medicines such as pregabalin, duloxetine or amitriptyline.
03. Foot care
Daily checks, good footwear and regular podiatry.
Frequently Asked Questions
Can nerve damage be reversed?
Why check my feet every day?
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Peripheral Nerve Disorders(opens in a new tab) · MedlinePlus, US National Library of Medicine
- Peripheral neuropathy(opens in a new tab) · NHS