AntibioticPrescription only

Doxycycline

Capsule or tablet

Quick Summary

Doxycycline works against a wide range of bacteria and some parasites.

Scrub typhus and leptospirosis
Acne
Chlamydia
Chest infections

Medical Uses

Scrub typhus and leptospirosis: First-choice treatment.
Acne: Moderate to severe.
Chlamydia: And other STIs.
Chest infections: Some types.

How it's taken

Swallow with a full glass of water while sitting or standing, and don't lie down for 30 minutes.

Take it for the full course, even if you feel better, unless your doctor tells you otherwise. Don't share antibiotics or keep leftovers.

Your doctor decides the right dose for you and how long to take it.

Your doctor decides the right dose for you. Follow their instructions and the label.

Common Side Effects

Nausea

Take with food if needed.

Sun sensitivity

Use sunscreen.

Heartburn

If the capsule sticks in the throat.

Interactions

Antacids, iron, calcium and dairy

Reduce absorption.

Warfarin

Bleeding risk.

Critical Warnings

Pregnancy and young children

Black Box Warning: Not used in pregnancy or children under 8 (stains teeth).

Sun sensitivity

Avoid strong sunlight.

Severe allergic reaction

Black Box Warning: Swelling of the face or throat, difficulty breathing or a widespread rash: get emergency help.

Antibiotic resistance

Using antibiotics when they aren't needed makes them less effective for everyone.

Sources and further reading

Last updated 21 October 2026. For more detail, see these trusted health organisations.

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