Haematology• Updated 21 October 2026
Sickling Test (Solubility Test)
A quick screening blood test for sickle haemoglobin.
Results: Same day Specimen: Blood
Quick Summary
Primary Purpose
To screen for sickle cell trait or disease, for example in community programmes.
What It Measures
Presence of sickle haemoglobin.
Preparation
No preparation.
Overview
It doesn't tell trait from disease; HPLC or electrophoresis confirms.
Used in India's sickle cell screening mission.
What It Measures
Sickle haemoglobin
Present or absent.
How It's Performed
- 01
Sample
Blood from a vein or finger.
- 02
Test
Solubility test.
- 03
Confirm
Positive results confirmed by HPLC.
Interpreting Results & Next Steps
Discuss with Doctor
Your doctor will explain what your result means and what happens next.
If values are High:
A positive screen needs a confirmatory test.
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Hemoglobin Electrophoresis(opens in a new tab) · MedlinePlus, US National Library of Medicine