Paracetamol
Tablet, syrup or suppository
Quick Summary
Paracetamol relieves mild to moderate pain and lowers fever. It's one of the most widely used medicines and is safe when taken as directed.
Medical Uses
How it's taken
Take it as directed on the label or by your doctor, leaving enough time between doses.
Check other medicines (such as cold remedies) for paracetamol so you don't take too much.
Your doctor decides the right dose for you. Follow their instructions and the label.
Common Side Effects
Few side effects
Usually well tolerated at normal doses.
Rash
Rarely, an allergic rash.
Liver damage
Only with too much paracetamol or with heavy alcohol use.
Interactions
Other medicines containing paracetamol
Many cold and flu remedies contain it; taking both can cause overdose.
Alcohol
Heavy drinking increases the risk of liver damage.
Warfarin
Regular paracetamol use can affect blood clotting tests.
Critical Warnings
Overdose
Black Box Warning: Taking too much can cause serious liver damage, even if you feel well at first. Get urgent help after an overdose.
Liver disease
Ask your doctor before using it if you have liver disease or drink heavily.
Sources and further reading
Last updated 21 October 2026. For more detail, see these trusted health organisations.
- Acetaminophen: drug information(opens in a new tab) · MedlinePlus, US National Library of Medicine
- Paracetamol for adults: painkiller for pain and high temperature(opens in a new tab) · NHS